Open-source tools for clinical risk prediction research

A short listicle for labs and courses exploring EHR risk prediction and clinical machine learning. Entries are illustrative—not a ranking of clinical products.

  1. EHR Risk Framework — Leakage-aware workbench (Docker + Angular + FastAPI), calibration, SHAP, research jobs. Docs · GitHub
  2. scikit-learn / XGBoost ecosystems — Core ML libraries; pair with careful temporal validation yourself.
  3. SHAP / interpretability libraries — Model explanations used inside many research pipelines.
  4. OMOP / FHIR tooling — Common data models and interchange for multi-site research (adapters vary by project).
  5. PhysioNet credentialed datasets (e.g. MIMIC) — Data access for eligible researchers—not a modeling framework; never commit PHI.

Related: Alternatives to opaque AutoML · Limitations